Molecular oncogenetics of metastasis.

  title={Molecular oncogenetics of metastasis.},
  author={T. Neil Dear and Richard F. Kefford},
  journal={Molecular aspects of medicine},
  volume={11 4},
Metastasis is a complex non-stochastic process that is most likely the result of genetic and epigenetic interactions of a wide variety of genes. The search for a single gene which can encompass such a pleiotropic response as to account for the observed phenotypic characteristics of metastatic tumour populations has been unsuccessful. Particular studies involving gene transfection, subtractive hybridisation and cell fusion are beginning to identify specific genes which contribute to metastasis… CONTINUE READING

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