Molecular modulators of the circadian clock: lessons from flies and mice

@article{MendozaViveros2016MolecularMO,
  title={Molecular modulators of the circadian clock: lessons from flies and mice},
  author={Lucia Mendoza-Viveros and Pascale Bouchard-Cannon and Sara Hegazi and Arthur H H Cheng and Stephen Pastore and Hai-Ying Mary Cheng},
  journal={Cellular and Molecular Life Sciences},
  year={2016},
  volume={74},
  pages={1035-1059}
}
Circadian timekeeping is a ubiquitous mechanism that enables organisms to maintain temporal coordination between internal biological processes and time of the local environment. The molecular basis of circadian rhythms lies in a set of transcription–translation feedback loops (TTFLs) that drives the rhythmic transcription of core clock genes, whose level and phase of expression serve as the marker of circadian time. However, it has become increasingly evident that additional regulatory… CONTINUE READING

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