Molecular modeling of cytochrome b₅ with a single cytochrome c-like thioether linkage.


Bovine liver cytochrome b (5) (cyt b (5)), with heme bound noncovalently, has been converted into a cyt c-like protein (cyt b (5) N57C) by constructing a thioether linkage between the heme and the engineered cysteine residue. With no X-ray or NMR structure available, we herein performed a molecular modeling study of cyt b (5) N57C. On the other hand, using… (More)
DOI: 10.1007/s00894-011-1189-y