Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens.

@article{Ruediger1994MolecularMO,
  title={Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens.},
  author={Ralf Ruediger and Marc Hentz and J. Fait and Marc C. Mumby and Gero Walter},
  journal={Journal of virology},
  year={1994},
  volume={68 1},
  pages={
          123-9
        }
}
Protein phosphatase 2A consists of three subunits, the catalytic subunit (C) and two regulatory subunits (A and B). The A subunit has a rod-like shape and consists of 15 nonidentical repeats. It binds the catalytic subunit through repeats 11 to 15 at the C terminus and the tumor antigens encoded by small DNA tumor viruses through overlapping but distinct regions at N-terminal repeats 2 to 8. A model of the A subunit was developed on the basis of the fact that uncharged or hydrophobic amino… CONTINUE READING

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