Molecular mimicry between virus and host and its implications for dengue disease pathogenesis.

@article{Lin2011MolecularMB,
  title={Molecular mimicry between virus and host and its implications for dengue disease pathogenesis.},
  author={Yee-Shin Lin and Trai-Ming Yeh and Chiou-Feng Lin and S. Wan and Yung-Chun Chuang and Tan-Kuei Hsu and Hsiao-Sheng Liu and C Liu and Robert Anderson and Huan-Yao Lei},
  journal={Experimental biology and medicine},
  year={2011},
  volume={236 5},
  pages={
          515-23
        }
}
Numerous infectious agents may trigger autoimmunity or even result in autoimmune diseases. Several mechanisms have been proposed for pathogen-triggered autoimmunity including molecular mimicry, cryptic antigens, epitope spreading, bystander activation and polyclonal activation. In the case of dengue virus infection which causes serious public health problems, the mechanisms regarding the pathogenesis of dengue hemorrhagic syndrome are not fully resolved. Our previous studies suggest a mechanism… CONTINUE READING

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