Molecular mimicry: anti-DNA antibodies bind microbial and nonnucleic acid self-antigens.

Abstract

Although cells of the innate immune response have a variety of pattern recognition receptors that are triggered by blood classes of markers, a critical feature of the adaptive immune response is antigenic specificity. Yet it is becoming increasingly clear that the specificity of lymphocyte receptors admits of some laxity. Cross-reactivity may, in fact, be… (More)

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