Molecular medicine of TFF-peptides: from gut to brain.

@article{Hoffmann2001MolecularMO,
  title={Molecular medicine of TFF-peptides: from gut to brain.},
  author={W. Hoffmann and Wolfgang Jagla and Antje Wiede},
  journal={Histology and histopathology},
  year={2001},
  volume={16 1},
  pages={319-34}
}
TFF-peptides (i.e. TFF1, TFF2, TFF3; formerly P-domain peptides, trefoil factors) have been established as secretory products typical of the gastrointestinal tract. Their synthesis has recently been recognized in a number of mucin-producing epithelial cells, for example, of the respiratory tract, the salivary glands, the uterus and of the conjunctiva. They have a pivotal role in maintaining the surface integrity of these delicate epithelia as constituents of mucus gels as well as by their anti… CONTINUE READING

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