Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB

Abstract

Osteoarthritis (OA) is a multi-factorial and highly prevalent joint disorder worldwide. Since the establishment of murine surgical knee OA models in 2005, many of the key molecules and signalling pathways responsible for OA development have been identified. Here we review the roles of two multi-functional signalling pathways in OA development: Notch and… (More)
DOI: 10.1186/s13075-017-1296-y

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Cite this paper

@inproceedings{Saito2017MolecularMU, title={Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB}, author={Taku Saito and Sakae Tanaka}, booktitle={Arthritis research & therapy}, year={2017} }