Molecular mechanisms underlying group A streptococcal pathogenesis.

  title={Molecular mechanisms underlying group A streptococcal pathogenesis.},
  author={Randall Olsen and Samuel A. Shelburne and James M. Musser},
  journal={Cellular microbiology},
  volume={11 1},
Group A Streptococcus (GAS) is a versatile human pathogen causing diseases ranging from uncomplicated mucosal infections to life-threatening invasive disease. The development of human-relevant animal models of GAS infection and introduction of new technologies have markedly accelerated the pace of discoveries related to GAS host-pathogen interactions. For example, recently investigators have identified pili on the GAS cell surface and learned that they are key components for adherence to… CONTINUE READING

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