Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides

@article{Calvieri2011MolecularMU,
  title={Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides},
  author={Camilla Calvieri and Speranza Rubattu and Massimo Volpe},
  journal={Journal of Molecular Medicine},
  year={2011},
  volume={90},
  pages={5-13}
}
Natriuretic peptides (NPs) exert well-characterized protective effects on the cardiovascular system, such as vasorelaxation, natri- and diuresis, increase of endothelial permeability, and inhibition of renin–angiotensin–aldosterone system. It has been reported that they also possess antihypertrophic and antifibrotic properties and contribute actively to cardiac remodeling. As a consequence, they are involved in several aspects of cardiovascular diseases. Antihypertrophic and antifibrotic… CONTINUE READING
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