Molecular mechanisms underlying anorexia nervosa: Focus on human gene association studies and systems controlling food intake

  title={Molecular mechanisms underlying anorexia nervosa: Focus on human gene association studies and systems controlling food intake},
  author={M. Rask-Andersen and Pawel K. Olszewski and Allen S. Levine and Helgi B. Schi{\"o}th},
  journal={Brain Research Reviews},
  • M. Rask-Andersen, Pawel K. Olszewski, +1 author Helgi B. Schiöth
  • Published 2010
  • Psychology, Medicine
  • Brain Research Reviews
  • Anorexia nervosa (AN) is a complex multi-factorial disease with high heritability. The psychological AN symptoms are poorly connected with specific molecular mechanisms. Here we review the molecular basis of AN with the focus on human genetic association studies; we put these in the experimental biological context with emphasis on molecular systems controlling food intake and body weight in a direct or indirect manner. We systematically searched for human genetic studies related to AN and… CONTINUE READING
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