Molecular mechanisms that confer antibacterial drug resistance

  title={Molecular mechanisms that confer antibacterial drug resistance},
  author={Christopher Walsh},
Antibiotics — compounds that are literally ‘against life’ — are typically antibacterial drugs, interfering with some structure or process that is essential to bacterial growth or survival without harm to the eukaryotic host harbouring the infecting bacteria. We live in an era when antibiotic resistance has spread at an alarming rate and when dire predictions concerning the lack of effective antibacterial drugs occur with increasing frequency. In this context it is apposite to ask a few simple… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 59 references

Drugs for HIV infection

W. Witte
Med . Lett . • 2000

Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant gram-positive bacterial infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2000

DNA gyrase as a drug target.

Biochemical Society transactions • 1999

Deconstructing vancomycin

A. L. Barry, P. C. Fuchs
Science • 1999

Engineering a methymycin / pikromycin - calicheamicin hybrid : construction of two new macrolides carrying a designed sugar moiety

D. M. Schlaes
J . Am . Chem . Soc . • 1999

The choice of antibacterial drugs

M. L. Nelson, B. H. Park, S. B. Levy
Med . Lett . • 1999

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