Molecular mechanisms of therapeutic hypothermia on neurological function in a swine model of cardiopulmonary resuscitation.

@article{Zhao2012MolecularMO,
  title={Molecular mechanisms of therapeutic hypothermia on neurological function in a swine model of cardiopulmonary resuscitation.},
  author={Hong Zhao and Chun-Sheng Joseph Li and Ping Gong and Zi-Ren Tang and Rong Hua and Xue Mei and Ming-Yue Zhang and Juan Cui},
  journal={Resuscitation},
  year={2012},
  volume={83 7},
  pages={913-20}
}
OBJECTIVE To explore the molecular mechanisms by which mild hypothermia following resuscitation improves neurological function in a porcine model of cardiac arrest. METHODS Thirty-three inbred Chinese Wuzhishan (WZS) minipigs were used. After 8 min of untreated ventricular fibrillation (VF), the surviving animals (n=29) were randomly divided into two groups including serum group (n=16) and molecular group (n=13). Serum group animals were used to measure porcine-specific tumour necrosis factor… CONTINUE READING

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Mild Hypothermia Protects Pigs’ Gastric Mucosa After Cardiopulmonary Resuscitation via Inhibiting Interleukin 6 (IL-6) Production

Medical science monitor : international medical journal of experimental and clinical research • 2016
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Mild hypothermia inhibits systemic and cerebral complement activation in a swine model of cardiac arrest.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2015

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