Molecular mechanisms of pituitary differentiation and regulation: implications for hormone deficiencies and hormone resistance syndromes.

@article{Drouin2006MolecularMO,
  title={Molecular mechanisms of pituitary differentiation and regulation: implications for hormone deficiencies and hormone resistance syndromes.},
  author={Jacques Drouin},
  journal={Frontiers of hormone research},
  year={2006},
  volume={35},
  pages={74-87}
}
During the last century, the questions posed by scientists and clinicians on pituitary function have led to new concepts about the mechanisms of hormone action and cell differentiation. In particular, the advent of molecular genetics and the cloning of pituitary hormone coding genes followed by discovery of their regulators during the last 20 years has provided tremendous insight into the pathophysiological bases of hormone deficit and excess, as well as offering novel therapeutic opportunities… CONTINUE READING

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