Molecular mechanisms of photodynamic therapy.

@article{Ortel2009MolecularMO,
  title={Molecular mechanisms of photodynamic therapy.},
  author={Bernhard Ortel and Christopher R. Shea and Piergiacomo Calzavara-Pinton},
  journal={Frontiers in bioscience},
  year={2009},
  volume={14},
  pages={
          4157-72
        }
}
Despite its more than 100-year history in experimental and clinical use, photodynamic therapy (PDT) is only starting to be appreciated for its full potential. PDT combines a photosensitizer (PS) and light in the presence of oxygen to treat cancer and other disorders. This manuscript reviews molecular mechanisms that have been evaluated over the past years for the effects of PDT at the cellular level as well as in therapeutic settings in vivo. The availability of multiple PS with different… CONTINUE READING

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