Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50.

@article{Driessler2004MolecularMO,
  title={Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50.},
  author={Frank Driessler and Kristine Venstrom and Robert Sabat and Khusru Asadullah and Arndt J G Schottelius},
  journal={Clinical and experimental immunology},
  year={2004},
  volume={135 1},
  pages={64-73}
}
Nuclear factor kappa B (NF-kappaB) is a transcription factor pivotal for the development of inflammation. A dysregulation of NF-kappaB has been shown to play an important role in many chronic inflammatory diseases including rheumatoid arthritis, inflammatory bowel disease and psoriasis. Although classical NF-kappaB, a heterodimer composed of the p50 and p65 subunits, has been well studied, little is known about gene regulation by other hetero- and homodimeric forms of NF-kappaB. While p65… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 71 extracted citations

Effect of low extracellular pH on NF-κB activation in macrophages☆

Atherosclerosis • 2014
View 16 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…