Molecular mechanisms of insulin resistance

@article{Schinner2005MolecularMO,
  title={Molecular mechanisms of insulin resistance},
  author={Sven Schinner and Werner A. Scherbaum and Stefan R. Bornstein and Andreas Barthel},
  journal={Diabetic Medicine},
  year={2005},
  volume={22}
}
Currently, we observe an epidemic expansion of diabetes mellitus. In subjects with Type 2 diabetes the resistance of fat, muscle and liver to insulin is the central pathophysiological event in the development of this disease. Genetic and environmental factors play a major role in this process, although the precise pathogenesis of insulin resistance and Type 2 diabetes is still largely unknown. However, recent studies have contributed to a deeper understanding of the molecular mechanisms… 
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