Molecular mechanisms of gonadotrophin releasing hormone-stimulated gonadotrophin secretion.

Abstract

Hypothalamic gonadotrophin releasing hormone (GnRH) exerts its effect on gonadotrophin synthesis and release via plasma membrane-bound receptors. The exocytosis of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) is activated by the binding of GnRH or its agonists to receptors in pituitary cells, which initiates a number of post-receptor… (More)

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