• DOI:10.1016/j.mce.2007.05.019
Corpus ID: 4121936

Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists

@article{Stahn2007MolecularMO,
  title={Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists},
  author={Cindy Stahn and M. L{\"o}wenberg and D. Hommes and F. Buttgereit},
  journal={Molecular and Cellular Endocrinology},
  year={2007},
  volume={275},
  pages={71-78}
}

Cindy Stahn, M. Löwenberg, +1 author F. Buttgereit

Published 2007

Biology, Medicine

Molecular and Cellular Endocrinology

Glucocorticoids (GC) are the most common used anti-inflammatory and immunosuppressive drugs in the treatment of rheumatic and other inflammatory diseases. Their therapeutic effects are considered to be mediated by four different mechanisms of action: the classical genomic mechanism of action caused by the cytosolic glucocorticoid receptor (cGCR); secondary non-genomic effects which are also initiated by the cGCR; membrane-bound glucocorticoid receptor (mGCR)-mediated non-genomic effects; non… CONTINUE READING

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