Molecular mechanisms of genetic disorders of keratinization.


An attempt is made to organize our current knowledge about genetically determined disorders of keratinized tissue, which primarily affect the epidermal structural proteins. Type I defects are those involving a change in a single amino acid and are analogous to sickle cell anemia. Type II defects are associated with abnormal retention of a normal structural… (More)


Cite this paper

@article{Goldsmith1976MolecularMO, title={Molecular mechanisms of genetic disorders of keratinization.}, author={Lowell A. Goldsmith}, journal={Archives of dermatology}, year={1976}, volume={112 3}, pages={375-8} }