Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression

@inproceedings{Wang2012MolecularMO,
  title={Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression},
  author={Hsiao-Chi Wang and Jung Pao and Shuw-Yuan Lin and L Sheen},
  booktitle={Annals of the New York Academy of Sciences},
  year={2012}
}
Skin cancer is a serious concern whose incidence is increasing at an alarming rate. Allyl sulfides-i.e., sulfur metabolites in garlic oil-have been demonstrated to have anticancer activity against several cancer types, although the mechanisms underlying these effects remain enigmatic. Our previous study showed that diallyl trisulfide (DATS) is more potent than mono- and disulfides against skin cancer. DATS inhibits cell growth of human melanoma A375 cells and basal cell carcinoma (BCC) cells by… CONTINUE READING
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