Molecular mechanisms of dendritic spine development and remodeling

  title={Molecular mechanisms of dendritic spine development and remodeling},
  author={I. Ethell and E. Pasquale},
  journal={Progress in Neurobiology},
  • I. Ethell, E. Pasquale
  • Published 2005
  • Biology, Medicine
  • Progress in Neurobiology
  • Dendritic spines are small protrusions that cover the surface of dendrites and bear the postsynaptic component of excitatory synapses. Having an enlarged head connected to the dendrite by a narrow neck, dendritic spines provide a postsynaptic biochemical compartment that separates the synaptic space from the dendritic shaft and allows each spine to function as a partially independent unit. Spines develop around the time of synaptogenesis and are dynamic structures that continue to undergo… CONTINUE READING
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