Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract.

@article{Bagchi2003MolecularMO,
  title={Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract.},
  author={Debasis Bagchi and Chandan K. Sen and Sidhartha D. Ray and Dipak Kumar Das and Manashi Bagchi and Harry G. Preuss and J. Andrew Vinson},
  journal={Mutation research},
  year={2003},
  volume={523-524},
  pages={87-97}
}
Free radicals and oxidative stress play a crucial role in the pathophysiology of a broad spectrum of cardiovascular diseases including congestive heart failure, valvular heart disease, cardiomyopathy, hypertrophy, atherosclerosis and ischemic heart disease. We have demonstrated that IH636 grape seed proanthocyanidin extract (GSPE) provides superior… CONTINUE READING