Molecular mechanisms of cannabinoid addiction

@article{Fratta2013MolecularMO,
  title={Molecular mechanisms of cannabinoid addiction},
  author={Walter Fratta and Liana Fattore},
  journal={Current Opinion in Neurobiology},
  year={2013},
  volume={23},
  pages={487-492}
}

Molecular Mechanisms of Cannabis Signaling in the Brain.

Cannabinoids: Drug or Medication?

The historical use of cannabis as a natural cure in ancient civilizations is described and the current use of cannabinoids in medicine, which includes innovative strategies for treating various diseases such as multiple sclerosis or cancer‐induced pain is explored.

Chapter 10 Cannabinoids : Drug or Medication ?

The historical use of cannabis as a natural cure in ancient civilizations is described and the current use of cannabinoids in medicine, which includes innovative strategies for treating various diseases such as multiple sclerosis or cancer‐induced pain is explored.

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Peripherally Restricted Cannabinoids for the Treatment of Pain

The scientific evidence to target the peripheral cannabinoid system as an alternative to cannabis use for medical purposes is discussed, and the available literature is reviewed to determine the pros and cons of potential strategies that can be used to this end.

Keep off the grass? Cannabis, cognition and addiction

The current state of knowledge about vulnerability factors, the variations in types of cannabis, and the relationship between these and cognition and addiction are reviewed.

Cannabinoid abuse and addiction: Clinical and preclinical findings

This review describes efforts to understand the mechanisms of cannabinoid abuse and its adverse effects, to identify molecular targets for pharmacotherapy, and to evaluate potential treatments in human volunteers and animal models of cannabinoid reward, withdrawal, and relapse.

The Modulating Role of Sex and Anabolic-Androgenic Steroid Hormones in Cannabinoid Sensitivity

The recent discovery that pregnenolone, the precursor of all steroid hormones, controls cannabinoid receptor activation corroborates the link between steroid hormones and the endocannabinoid system.

Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders

Recent progress in research regarding the endocannabinoid systems, cannabis reward versus aversion, and the underlying receptor mechanisms is reviewed, and cannabinoid-based medication development for the treatment of SUDs is reviewed.

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