Molecular mechanisms of cannabinoid addiction

  title={Molecular mechanisms of cannabinoid addiction},
  author={W. Fratta and L. Fattore},
  journal={Current Opinion in Neurobiology},
  • W. Fratta, L. Fattore
  • Published 2013
  • Psychology, Medicine
  • Current Opinion in Neurobiology
  • Cannabis is the world's most widely used illicit substance, with an estimated number of 119-224 million users worldwide. In recent years we assisted to an increased effort aimed to individuate the brain circuits underlying cannabis addiction and dependence. Similarly to other drugs of abuse, repeated exposure to cannabinoids causes brain neuroadaptations that persist long after drug effects, contribute to the negative affective states during withdrawal, and ultimately facilitate relapse… CONTINUE READING
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