Molecular mechanisms of bacterial quorum sensing as a new drug target.

  title={Molecular mechanisms of bacterial quorum sensing as a new drug target.},
  author={Hiroaki Suga and Kristina M Smith},
  journal={Current opinion in chemical biology},
  volume={7 5},
Bacterial quorum sensing evolved as a means for bacterial communities to rapidly and coordinately change genome expression patterns in response to environmental cues. Each cell in a community produces and responds to a signaling molecule called an autoinducer that serves as an indicator of the population density. A high concentration of autoinducer is associated with a large, often confined population, which requires altered gene expression for survival. Quorum sensing is one mechanism through… CONTINUE READING

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