Molecular mechanisms of apoptosis and roles in cancer development and treatment.

  title={Molecular mechanisms of apoptosis and roles in cancer development and treatment.},
  author={Samira Goldar and Mahmoud Shekari Khaniani and Sima Mansoori Derakhshan and Behzad Baradaran},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  volume={16 6},
Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all multicellular organisms to control cell proliferation and maintain tissue homeostasis as well as eliminate harmful or unnecessary cells from an organism. Defects in the physiological mechanisms of apoptosis may contribute to different human diseases like cancer. Identification of the mechanisms of apoptosis and its effector proteins as well as the genes responsible for apoptosis has provided a new opportunity to… CONTINUE READING
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