Molecular mechanisms of angiotensin II in modulating cardiac function: intracardiac effects and signal transduction pathways.

@article{Dostal1997MolecularMO,
  title={Molecular mechanisms of angiotensin II in modulating cardiac function: intracardiac effects and signal transduction pathways.},
  author={David E. Dostal and Rachel A Hunt and Chris E Kule and G. Jayarama Bhat and Vijaya Karoor and Charlene D. McWhinney and Kenneth M. Baker},
  journal={Journal of molecular and cellular cardiology},
  year={1997},
  volume={29 11},
  pages={2893-902}
}
Angiotensin II (Ang II), the effector peptide of the renin-angiotensin system (RAS), regulates volume and electrolyte homeostasis and is involved in cardiac and vascular cellular growth in humans and other species. This system, which has been conserved throughout evolution, plays an important role in cardiac and vascular pathology associated with hypertension, coronary heart disease, myocarditis and congestive heart failure. The traditional RAS is viewed as a system in which circulating Ang II… CONTINUE READING

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