Molecular mechanisms of Staphylococcus aureus iron acquisition.

  title={Molecular mechanisms of Staphylococcus aureus iron acquisition.},
  author={Neal D. Hammer and Eric P Skaar},
  journal={Annual review of microbiology},
The unique redox potential of iron makes it an ideal cofactor in diverse biochemical reactions. Iron is therefore vital for the growth and proliferation of nearly all organisms, including pathogenic bacteria. Vertebrates sequester excess iron within proteins in order to alleviate toxicity and restrict the amount of free iron available for invading pathogens. Restricting the growth of infectious microorganisms by sequestering essential nutrients is referred to as nutritional immunity. In order… CONTINUE READING


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