Molecular mechanisms of PKC [ delta ] in neurotoxin-induced apoptotic death of nigral dopaminergic neurons : relevance to the pathogenesis of Parkinson ' s disease

v CHAPTER I: GENERAL INTRODUCTION 1 Dissertation Organization 1 Research Objective 2 Background and Literature Review 3 CHAPTER II: SUPPRESSION OF CASPASE-3 DEPENDENT PROTEOLYTIC ACTIVATION OF PROTEIN KINASE C5 BY SMALL INTERFERING RNA (SIRNA) PREVENTS MPP+-INDUCED DOPAMINERGIC DEGENERATION 57 Abstract 57 Introduction 58 Results 60 Discussion 68 Materials… CONTINUE READING