Molecular mechanisms of Escherichia coli pathogenicity

  title={Molecular mechanisms of Escherichia coli pathogenicity},
  author={Matthew A. Croxen and B. Brett Finlay},
  journal={Nature Reviews Microbiology},
Escherichia coli is a remarkable and diverse organism. This normally harmless commensal needs only to acquire a combination of mobile genetic elements to become a highly adapted pathogen capable of causing a range of diseases, from gastroenteritis to extraintestinal infections of the urinary tract, bloodstream and central nervous system. The worldwide burden of these diseases is staggering, with hundreds of millions of people affected annually. Eight E. coli pathovars have been well… 
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