Molecular mechanisms of ANP inhibition of renal sodium transport.

@article{Stanton1991MolecularMO,
  title={Molecular mechanisms of ANP inhibition of renal sodium transport.},
  author={Bruce A. Stanton},
  journal={Canadian journal of physiology and pharmacology},
  year={1991},
  volume={69 10},
  pages={1546-52}
}
  • Bruce A. Stanton
  • Published 1991 in Canadian journal of physiology and pharmacology
ANP, a hormone secreted by the atria of mammalian hearts in response to volume expansion, increases urinary sodium excretion in part by inhibiting sodium reabsorption across the inner medullary collecting duct. A number of nephron segments may contribute to the ANP-induced natriuresis; however, this review will focus on the cellular mechanisms of ANP inhibition of electrogenic sodium reabsorption by the inner medullary collecting duct. Patch-clamp studies conducted on rat inner medullary… CONTINUE READING
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