Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals.

  title={Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals.},
  author={Bryan A. Ballif and John Blenis},
  journal={Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research},
  volume={12 8},
Introduction To maximize advantages and reduce costs associated with life as an interdependent community of cells, multicellular organisms have evolved common mechanisms to regulate the life and death of their individual cells. Critical to the health and survival of a multicellular organism is its ability to selectively sustain advantageous cells and selectively eliminate cells that threaten the survival of its cellular community. Therefore, regulated survival of individual cells evolved in a… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 173 extracted citations


Publications referenced by this paper.
Showing 1-10 of 175 references

Identification of a novel inhibitor of mitogen-activated protein kinase kinase.

The Journal of biological chemistry • 1998
View 11 Excerpts
Highly Influenced

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1999
View 13 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…