Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences

@article{Lu2001MolecularMF,
  title={Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences},
  author={Aiping Lu and Anu Gupta and C Li and Thomas E. Ahlborn and Yongsheng Ma and Eric Y Shi and Jingwen Liu},
  journal={Oncogene},
  year={2001},
  volume={20},
  pages={5173-5185}
}
Breast cancer specific gene 1 (BCSG1), also referred as synuclein γ, is the third member of a neuronal protein family synuclein. BCSG1 is not expressed in normal breast tissues but highly expressed in advanced infiltrating breast carcinomas. When over expressed, BCSG1 significantly stimulates breast cancer metastasis. To elucidate the molecular mechanisms underlying the abnormal transcription of BCSG1 in breast cancer cells, in this study, we isolated a 2195 base pair fragment of human BCSG1… CONTINUE READING
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References

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Showing 1-4 of 4 references

Proc

  • T.
  • Natl. Acad. Sci. USA., 90, 11282 ± 11286. Xia Y…
  • 1993
Highly Influential
4 Excerpts

Science, 276, 2045 ± 2047

  • R. Nussbaum
  • Robertson K and Wol€e A. (2000). Nature Genetics…
  • 1997

J

  • S Kudo, M. Fukuda
  • Biol. Chem., 270, 13298 ± 13302.
  • 1995
1 Excerpt

Biochem

  • A Feinberg, B. Vogelstein
  • Biophy. Rea.
  • 1983
2 Excerpts

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