Molecular mechanisms and imaging of lymphatic metastasis.

  title={Molecular mechanisms and imaging of lymphatic metastasis.},
  author={Steven T Proulx and Michael Detmar},
  journal={Experimental cell research},
  volume={319 11},
In many types of cancer, tumors metastasize through the lymphatic system to draining lymph nodes. These sentinel lymph nodes have gained increased attention as a prognostic indicator for the severity of the disease, leading to the sentinel lymph node mapping and biopsy procedure to be accepted as standard-of-care for breast cancer and melanoma. However, many limitations exist with this procedure resulting in high false negative rates. In this review we highlight the new advances in the… CONTINUE READING
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  • S. T. Proulx, P. Luciani, A. Alitalo
  • Mumprecht, J., C.A. Huggenberger, R. Leroux, J.C…
  • 2013
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