Molecular mechanism of hippocampal apoptosis of mice following exposure to titanium dioxide nanoparticles.

@article{Hu2011MolecularMO,
  title={Molecular mechanism of hippocampal apoptosis of mice following exposure to titanium dioxide nanoparticles.},
  author={Renping Hu and Lei Zheng and Ting Zhang and Guodong Gao and Yaling Cui and Zhe Cheng and Jie Cheng and Mengmeng Hong and Meng Tang and Fashui Hong},
  journal={Journal of hazardous materials},
  year={2011},
  volume={191 1-3},
  pages={32-40}
}
Previous studies demonstrate that the exposure to titanium dioxide nanoparticles (TiO(2) NPs) damages the central nervous system of mice; however, very little is known about the effects of TiO(2) NPs on hippocampal apoptosis or its molecular mechanism. The present study investigated the molecular mechanism associated with hippocampal apoptosis in mice induced by intragastric administration of TiO(2) NPs for consecutive 60 days. Our findings indicate that TiO(2) NPs accumulate in the mouse… CONTINUE READING
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