Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent.

@article{Srinivas2007MolecularMO,
  title={Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent.},
  author={Gopal Srinivas and Suboj Babykutty and Priya Prasanna Sathiadevan and Priya Srinivas},
  journal={Medicinal research reviews},
  year={2007},
  volume={27 5},
  pages={591-608}
}
Anthraquinones represent a large family of compounds having diverse biological properties. Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a naturally occurring anthraquinone present in the roots and barks of numerous plants, molds, and lichens, and an active ingredient of various Chinese herbs. Earlier studies have documented mutagenic/genotoxic effects of emodin, mainly in bacterial system. Emodin, first assigned to be a specific inhibitor of the protein tyrosine kinase p65lck, has now a… CONTINUE READING
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