Molecular mechanism and structure of Trigger

Abstract

Ribosome-associated chaperone Trigger Factor (TF) initiates folding of newly synthesized proteins in bacteria. Here, we pinpoint by site-specific crosslinking the sequence of molecular interactions of Escherichia coli TF and nascent chains during translation. Furthermore, we provide the first full-length structure of TF associated with ribosome–nascent… (More)

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Cite this paper

@inproceedings{Merz2008MolecularMA, title={Molecular mechanism and structure of Trigger}, author={F. Merz and Daniel B{\"o}hringer and Christiane Schaffitzel and Steffen Preissler and Anja Hoffmann and Timm Maier and Anna Rutkowska and Jasmin Lozza and Nenad Ban and Bernd Bukau}, year={2008} }