Molecular markers in stored kidneys using perfluorocarbon-based preservation solution: preliminary results.

@article{Maluf2006MolecularMI,
  title={Molecular markers in stored kidneys using perfluorocarbon-based preservation solution: preliminary results.},
  author={Daniel G. Maluf and Valeria R. Mas and Kenneth C Yanek and James W. Stone and Ricardo Weis and Davis H Massey and Bruce Spiess and Marc P. Posner and Robert A. Fisher},
  journal={Transplantation proceedings},
  year={2006},
  volume={38 5},
  pages={1243-6}
}
BACKGROUND Delayed graft function (DGF) is a problem in kidney transplantation and cold ischemia has been identified as a risk factor. Perfluorocarbons (PFC) have an enhanced ability to dissolve and release oxygen. We evaluated histologically and a number of molecular changes induced by ischemia in stored kidneys with University of Wisconsin (UW) and PFC-based preservation solutions (PFC-UW). MATERIALS AND METHODS ACI rats were used as kidney donors. UW (control group) or PFC-UW (study group… CONTINUE READING