Molecular markers in circulating tumour cells from metastatic colorectal cancer patients

@inproceedings{Gazzaniga2010MolecularMI,
  title={Molecular markers in circulating tumour cells from metastatic colorectal cancer patients},
  author={Paola Gazzaniga and Angela Gradilone and Arianna Petracca and Chiara Nicolazzo and Cristina Raimondi and Roberto Iacovelli and G. Naso and Enrico Cortesi},
  booktitle={Journal of cellular and molecular medicine},
  year={2010}
}
The prognosis of metastatic cancer patients is still largely affected by treatment failure, mainly due to drug resistance. The hypothesis that chemotherapy might miss circulating tumour cells (CTCs) and particularly a subpopulation of more aggressive, stem-like CTCs, characterized by multidrug resistance, has been recently raised. We investigated the prognostic value of drug resistance and stemness markers in CTCs from metastatic colorectal cancer patients treated with oxaliplatin (L-OHP) and 5… CONTINUE READING

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