Molecular markers for the diagnosis and management of ductal carcinoma in situ.

@article{Polyk2010MolecularMF,
  title={Molecular markers for the diagnosis and management of ductal carcinoma in situ.},
  author={Korn{\'e}lia Poly{\'a}k},
  journal={Journal of the National Cancer Institute. Monographs},
  year={2010},
  volume={2010 41},
  pages={210-3}
}
Ductal carcinoma in situ (DCIS) is a heterogeneous group of lesions reflecting the proliferation of malignant cells within the ducts of the breast without invasion through the basement membrane. Numerous studies analyzing the molecular profiles of DCIS using genome-wide unbiased and candidate gene approaches have been conducted with the aim of identifying clinically useful markers that would predict the risk of progression to invasion. Results of these investigations defined the heterogeneity… CONTINUE READING
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