Molecular links between mitochondrial dysfunctions and schizophrenia

@article{Park2012MolecularLB,
  title={Molecular links between mitochondrial dysfunctions and schizophrenia},
  author={C. Park and S. K. Park},
  journal={Molecules and Cells},
  year={2012},
  volume={33},
  pages={105-110}
}
  • C. Park, S. K. Park
  • Published 2012
  • Medicine, Biology
  • Molecules and Cells
  • Schizophrenia is a complex neuropsychiatric disorder with both neurochemical and neurodevelopmental components in the pathogenesis. Growing pieces of evidence indicate that schizophrenia has pathological components that can be attributable to the abnormalities of mitochondrial function, which is supported by the recent finding suggesting mitochondrial roles for Disrupted-in-Schizophrenia 1 (DISC1). In this minireview, we briefly summarize the current understanding of the molecular links between… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 71 REFERENCES
    Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
    • 549
    • Open Access
    Mitochondrial involvement in psychiatric disorders
    • 232
    • Open Access
    Mitochondrial complex i subunits expression is altered in schizophrenia: a postmortem study
    • 161
    Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development
    • 182
    • Open Access
    Mitochondria in Neuroplasticity and Neurological Disorders
    • 667
    • Open Access
    Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia
    • 156