Molecular karyotyping in patients with mental retardation using 100K single-nucleotide polymorphism arrays.

@article{Hoyer2007MolecularKI,
  title={Molecular karyotyping in patients with mental retardation using 100K single-nucleotide polymorphism arrays.},
  author={Juliane Hoyer and A. Dreweke and Christian M. Becker and Ina Goehring and Christian T Thiel and Maarit M Peippo and Ralf Rauch and Michael Hofbeck and Udo Trautmann and Christiane Zweier and Martin Zenker and Ulrike H{\"u}ffmeier and Cornelia Kraus and Arif B. Ekici and Franz R{\"u}schendorf and Peter N{\"u}rnberg and Andr{\'e} Reis and Anita Rauch},
  journal={Journal of medical genetics},
  year={2007},
  volume={44 10},
  pages={629-36}
}
BACKGROUND Using array techniques, it was recently shown that about 10% of patients with mental retardation of unknown origin harbour cryptic chromosomal aneusomies. However, data analysis is currently not standardised and little is known about its sensitivity and specificity. METHODS We have developed an electronic data analysis tool for gene-mapping SNP… CONTINUE READING