Molecular karyotyping and aneuploidy detection in Arabidopsis thaliana using quantitative fluorescent polymerase chain reaction.

@article{Henry2006MolecularKA,
  title={Molecular karyotyping and aneuploidy detection in Arabidopsis thaliana using quantitative fluorescent polymerase chain reaction.},
  author={Isabelle M Henry and Brian P Dilkes and Luca Comai},
  journal={The Plant journal : for cell and molecular biology},
  year={2006},
  volume={48 2},
  pages={307-19}
}
Certain cellular processes are sensitive to changes in gene dosage. Aneuploidy is deleterious because of an imbalance of gene dosage on a chromosomal scale. Identification, classification and characterization of aneuploidy are therefore important for molecular, population and medical genetics and for a deeper understanding of the mechanisms underlying dosage sensitivity. Notwithstanding recent progress in genomic technologies, limited means are available for detecting and classifying changes in… CONTINUE READING
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