Highly Influenced
6 Excerpts
Molecular integration of wingless, decapentaplegic, and autoregulatory inputs into Distalless during Drosophila leg development.
- Published 2008 in Developmental cell
Abstract
The development of the Drosophila leg requires both Decapentaplegic (Dpp) and Wingless (Wg), two signals that establish the proximo-distal (PD) axis by activating target genes such as Distalless (Dll). Dll expression in the leg depends on a Dpp- and Wg-dependent phase and a maintenance phase that is independent of these signals. Here, we show that accurate… (More)