Molecular instability of the mitochondrial haplogroup T sequences at nucleotide positions 16292 and 16296

  title={Molecular instability of the mitochondrial haplogroup T sequences at nucleotide positions 16292 and 16296},
  author={B. Malyarchuk and M. Derenko},
  journal={Annals of Human Genetics},
  • B. Malyarchuk, M. Derenko
  • Published 1999
  • Biology
  • Annals of Human Genetics
  • The mitochondrial haplogroup T, characterized by the nucleotide motif 16126C–16294T in the hypervariable segment I (HVS I), is one of the most frequent among Europeans. It has been shown that this haplogroup includes the only well‐resolved subgroup, T1, but that other HVS I sequences cannot be differentiated into subgroups due to possible homoplasies at nucleotide positions 16292, 16296 and 16304, leading to the reticulations in the topology of phylogenetic networks. To study the problem of… CONTINUE READING
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