Molecular insights into cancer invasion: strategies for prevention and intervention.

@article{Kohn1995MolecularII,
  title={Molecular insights into cancer invasion: strategies for prevention and intervention.},
  author={Elise C. Kohn and Lance A. Liotta},
  journal={Cancer research},
  year={1995},
  volume={55 9},
  pages={1856-62}
}
The diagnosis and treatment of solid tumors usually begins at a late stage when most patients already have occult or overt metastasis. Many years of cancer progression precede diagnosis of most solid tumors. Novel noncytotoxic therapeutics may be specially suited for administration during this interval. An important window of intervention can be defined as the period during which transition from a hyperproliferative state to acquisition of the capacity for invasion and metastasis occurs… CONTINUE READING
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