Molecular insights into cancer drug resistance from a proteomics perspective

  title={Molecular insights into cancer drug resistance from a proteomics perspective},
  author={Yao An and Li Zhou and Zhao Huang and Edouard C. Nice and Haiyuan Zhang and Canhua Huang},
  journal={Expert Review of Proteomics},
  pages={413 - 429}
ABSTRACT Introduction: Resistance to chemotherapy and development of specific and effective molecular targeted therapies are major obstacles facing current cancer treatment. Comparative proteomic approaches have been employed for the discovery of putative biomarkers associated with cancer drug resistance and have yielded a number of candidate proteins, showing great promise for both novel drug target identification and personalized medicine for the treatment of drug-resistant cancer. Areas… 

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