Molecular insights into allosteric modulation of Class C G protein-coupled receptors.

@article{Leach2017MolecularII,
  title={Molecular insights into allosteric modulation of Class C G protein-coupled receptors.},
  author={Katie Leach and Karen J. Gregory},
  journal={Pharmacological research},
  year={2017},
  volume={116},
  pages={105-118}
}
Class C G protein-coupled receptors (GPCRs) recognise diverse extracellular stimuli and are highly tractable drug targets for a host of different psychiatric, neurological and metabolic disorders. Discovery efforts focussed on allosteric modulators for Class C GPCRs have been highly fruitful, with diverse chemotypes identified for multiple Class C members… CONTINUE READING