Molecular imaging of proliferation in vivo: positron emission tomography with [18F]fluorothymidine.

Abstract

Deregulated cell cycle progression is a hallmark of cancer. Accordingly, a major part of therapeutic drugs has been designed to inhibit cell proliferation and tumor growth. Metabolic imaging with positron emission tomography (PET) and the glucose analog 2'-[(18)F]fluoro-2'-deoxyglucose (FDG) has been demonstrated to sensitively detect malignant tumors and… (More)
DOI: 10.1016/j.ymeth.2009.03.009

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