Molecular identities of mitochondrial Ca2+ influx mechanism: Updated passwords for accessing mitochondrial Ca2+-linked health and disease

Abstract

Introduction Mitochondrial Ca 2+ homeostasis is crucial for balancing cell survival and death (Giacomello et al., 2007; Duchen et al., 2008). Mitochondrial Ca 2+ uptake mechanisms across the inner mitochondrial membrane (IMM) are especially important for the regulation of ATP synthesis , the amplitude and spatiotemporal patterns of intra-cellular Ca 2… (More)
DOI: 10.1085/jgp.201210795

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